Round 8 - what are our chances?
1 Replies
kellym - November 12

Good Morning,
I am just about to have my 8th IVF transfer, each round has been using ICSI due to male factor. To give you a quick rundown of my situation
1st IVF - 12 eggs, 9 fertilized, 2 transferred (day 3), none to freeze - chemical
2nd IVF - 6 eggs, 1 fertilized, 1 transferred (day 3) - BFN
3rd IVF - 11 eggs, 8 fertilized, 3 transferred (day 3), the rest taken to blast but didn't make it - BFN
4th IVF - 12 eggs, 7 fertilized, 4 transferred (day 3), 3 frozen - chemical
5th IVF - 11 eggs, 10 fertilized, 6 made it to blast, 3 transferred (day 5), 3 frozen - BFN
6th IVF/FET - 3 thawed blasts - BFN
7th IVF - donor sperm - 5 eggs, 3 fertilized, 3 poor quality embryos transferred (day 3) - BFN

So, this is my 8th IVF and again we used donor sperm. They retrieved 10 eggs, 6 fertilized - on day 2 (today), there are 4 2-cell and 2 4-cell, all grade 1 embyros (little fragmentation). They are planning to do a 3 day transfer.

The other factor to consider is that after our 6th IVF we learned that my husband has 50% sperm fragmentation so for our 7th and 8th attempts we used donor sperm. For all of our transfers up to our 6th we were transferring 8 or 10 cell embryos which were either grade 1 or 2 - we've never had 4 cell embryos on day three prior to using donor sperm.

I've been tested for immunlogical problems, had a HSG, etc. They keep telling me that everything is fine with me and they don't know if it is my eggs.

Would you say that my husband's sperm fragmentation impacted our success of our 1st to 6th rounds?

Do you think we'll have any luck this round given our embryo development on day 2.

A brutally honest opinion is welcomed because I don't want any false hope after 7 failed attempts.


B. Jacobs, M. D. - November 12

I have no way of providing a valid opinion. Each program has different capabilities and weaknesses. We rarely do day 3 tranfers, because we can almost always relaibly grow embryos to blastocysts. Snice genes from sperm do not play a role until after day 3, we have theopportunity to "weed out" some of the sperm problems before tranfer.
Good luck.



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