Treating Female Fertility Issues: Urofollitropin (FSH)

If you and your partner are having difficulties becoming pregnant, your reproductive endocrinologist will likely examine a number of aspects of your reproductive health. In particular, she will evaluate your menstrual cycle and ovulation. Abnormalities in the ovulatory process can often make pregnancy difficult for some couples. If you are having difficulties ovulating regularly, your health care provider may recommend the use of a fertility drug, like Urofollitropin. Urofollitropin can help to regulate your ovulation and increase your chances of pregnancy.

What is Urofollitropin?
Urofollitropin is the name given to a purified form of FSH (follicle stimulating hormone). FSH is a hormone produced by a small gland found inside your brain, called the pituitary gland. It works on your ovaries to help stimulate folliclular development and ovulation.

Sometimes, women do not produce enough FSH to regularly stimulate the development of their follicles. As a result, FSH is given to these women in order to encourage the ovulatory process (known as ovulation induction). Typically, this FSH is made syntheticaly, in the form of recombinant FSH, or it is taken from the urine of post-menopausal women. However, this is a complicated process and it is often difficult to retrieve uncontaminated samples of the FSH. Urofollitropin is a type of FSH that has been completely purified, and is thus free from any contamination.

Who Can Benefit from Urofollitropin Therapy?
Urofollitropin therapy is often used to help women ovulate more regularly. Women who are experiencing ovulatory or menstrual cycle disorders may elect to take urofollitropin, especially if they haven't achieved a pregnancy while taking Clomid. Urofollitropin is commonly used by women suffering from:

  • low levels of FSH
  • elevated levels of LH (luteinizing hormone)
  • PCOS (polycystic ovarian syndrome)
  • anovulation
  • unexplained infertility

Urofollotropin is also used to help produce multiple eggs for:

  • IVF
  • GIFT
  • ZIFT 

How is Urofollitropin Taken?
Urofollitropin is generally given through intramuscular or subcutaneous injections. Typically, one injection of urofollitropin is given twice per day until ovulation is achieved. Dosages are different for every woman, but tend to range between 75 and 600 IU per day (or approximately one to eight ampules).


Table of Contents
1. Definition: Urofollitropin (FSH)
2. Is Urifollitropin dangerous?
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