Ovulation inducing medications such as clomid are usually the first course of treatment for unexplained infertility. You may be prescribed clomid and told to time sexual intercourse to coincide with ovulation, but it is more likely that you'll be given clomid and then offered IUI (intrauterine insemination) using your partner's semen. Clomid normally isn't prescribed for more than six months.
Usually, after around three attempts at IUI, you would be offered the chance to try IVF. IVF has been successful in treating couples with unexplained infertility if the woman is under 40 years old and tests of her ovarian reserves (how many eggs she has in her ovaries) have come back normal.
Getting A Second Opinion
Some fertility experts do not accept unexplained infertility as a legitimate diagnosis. They believe that a reason can be found through more extensive testing. Research is ongoing in this area. If you are not satisfied with your diagnosis, you're within your rights to seek a second opinion.