Please help - embryo division!!!
1 Replies
mummywannab - October 5


Oh thank god i've found this sight as i'm ever so concerned that i'm losing my mind...

I'm on my 2ww on my first IVF and i not feeled with much hope.

I had 21 follicles, 11 eggs collected - 5 fertilised. I had a day 3 transfer which to say the least didn't go as planned they were unable to get the catheter through my cervix and after some time of trying decided that the only way to get my embryos in was to make there own hole via a needle through the uterus wall.. this put me in extreme pain and distress but my embryos were on board.

My problem is before transfer the embryologist said that out of the 5 i had 3 which were grade 1 but were slow dividers (2 cell on day 2 and 4 cell on day 3) i had the best 2 put back and the rest were left to grow. The embryologist said that they may catch up once in their own environment or it could mean that they would stop in a couple of days!!!!

I had a call on day 5 from the embryoloigist who said that my remaining 3 hadn't made it to blastocyst but that one had almost made it which was promising.

I have since been trying to find info and success from having a day 3 transfer with 2 grade 1, 4 cell embryos and i would very much appreciate your opinions.

Are my chances very low???

Thank you for your time.. i really don't know where else to turn.

Kind regards, Vicky Scott.


Dr Smith - October 5

I have a couple of concerns. Trans-uterine embryo transfer doesn't work very well because, although the embryos may make it into the uterine cavity, the puncture wound will cause a blood clot inside the uterine cavity that may interfere with the attachment of the embryo and subsequent implantation. It is truely a last ditch attempt to transfer embryos. An uncooperative cervix can be spotted during a trial or "mock" transfer in the cycle preceeding the IVF cycle. Cervical dilators or laminaria may be used to open the cervical canal and facilitate the passage of the embryo catheter prior to the IVF embryo transfer. This makes for a much less traumatic (physically and psychologically) embryo transfer.

The second concern is the rate of growth of the embryos. Yes, they may "catch up", but they had not achieved the critical 8-cell stage. Most genetically abnormal embryos arrest development between the 4- and 8-cell stage of development. Since your embryos had not made it over that hurdle, it is dificult to say what you chances are.

Between the trans-uterine transfer and the slow developing embryos, it doesn't look good. I know that's not what you wanted to hear, but I call 'em as I see 'em. But, you never say never, So hang in there.



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