Prometrium suppositories or Progesterone shots?
4 Replies
|
|
|
|
|
|
Dr. Jacobs, I have had a terrible reaction to the PIO injections both IVF cycles. Was wondering what you would do with a patient that has an allergic reaction (not life threatening) to the shots? Would you recommend trying the pio for a few days until the reaction begins (which is tolerable) and then move to prometrium? Or would you recommend just starting with Prometrium OR would you recommend if I could tolerate the shots at all then stick with those because thats where the efficacy is?
Thanks so much
Carrie
|
|
|
|
|
|
|
|
Your reaction may be to the oil vehicle for the progesterone. It is common to use peanut oil, but some people are alergic to that. I have the pharmacy dispense progesterone in sesame oil. I have not seen a major reaction to that. Progesterone in oil is still the "gold standard", and I am too much of a coward to abandon it.
Good luck.
|
|
|
|
|
|
|
I too had a bad reaction to the sesame oil. My butt developed a red rash. I mean talk about itchin' my butt all day long!! ;D Even a month after stopping the shots!
Now if I was allergic to the oil would this have cause my biochemical? Probably not. I just want to rule this out. I am going to ask my nurse to give me progesterone suppositories along with the PIO shots. Would prescribing both be ok and not harmful? I mean better safe than sorry right? Double dosing on progesterone is ok right? My clinic does not do blood work on yuor pregesterone levels during the 2WW.
Thanks!
|
|
|
|
|
|
|
Using both an intramuscular and vaginal preparation is not a problem. No, the reaction to the sesame oil did nt cause the biochamical pregnancy.
Good luck.
|
|
|
|
|
|
|
Progesterone is the same hormone the ovary makes after ovulation and the placenta makes. They are chemically identical compounds, and the source is not relevant.
|
