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I have heard that women who are PCOS can have poor egg or embryo quality? Is there any consistent things you see with their egg morphology (grainy cytoplasm etc.) or embryos (slow cell division)?
Have you ever tried Metformin with a patient who does not have all the classic signs of PCOS (annovulation, overwt, high lh to fsh ratio etc.) but maybe has some of the signs (string of pearl appearance to ovaries, excess hair growth etc.) and therefore maybe a subclinical form of it? Has it helped?
If someone was prescribed Metformin for a possible subclinical form of PCO is there any way that it could negatively impact their egg or embryo quality further if it really wasn't needed or is it one of those situations where it cannot hurt but may not help either?
Thank you for your time.
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I routinely put all of my patients with polycystic ovaries on Glucophage. The generic, metformin, seems to produce more undesirable side effects. Good luck.
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