What are Donor Eggs chances?
1 Replies
BekyVice - December 14

Hello! Assuming husband's sperm is terrific, my uterine lining is superb, all my beta levels of every hormone needed in keeping an embryo in my uterus through an entire pregnancy are all perfectly where they should be.... what other factors would/could cause an IVF failure after using a proven donor's eggs in a 42-year-old (me)?

(Haven't used DE before, but before forking out yet another $30K, my husband wants to feel like this last resort will have at least a 60-70% chance or else we just can't afford it.)



Dr Smith - December 18

A 50-60% chence of taking home a baby from the hospital would be a reasonable expectation, if the following criteria are met:

1. There is realitively synchronous growth of the donor's follicles during the stimulation and the E2 is appropriate at the time of hCG (about 250 pg/ml for each mature follicle)
2. The donor provides 12-20 eggs and is NOT shared between two or more recipents
3. About 80% of the eggs are mature at the time of retrieval.
4. About 80% of mature eggs fertilize normally (one sperm - one egg)
5. About 50% of the resulting embryos make it to the blastocyst stage
6. Two high quality blastocyst stage embryos are transferred and any remaining embryos cryopreserved.

You can see there's a lot of "ifs" above and a lot of things have to go just right to get in the 50-60% of the couples that are successful from DEIVF. However, in a good program (i.e. one with a consistent 50-60% live birth rate from DEIVF), you can be confident that all these factors are being controlled as best they can. You can't control everything and sh** happens.

DEIVF provides the best chances of pregnancy for all ART treatments. Its expensive, but from a strictly financial viewpoint, its the best "bang for the buck".

A word about superlatives and IVF. I realize you were poking fun with all the superlatives in your post and I'm glad you made that point. Sometimes docs use supleratives, as you did above, and give patients a false sense of security and then, when sh** happens, the world caves in. It is important to maintain a realistic outlook, ever when you are bombarded with superlatives from docs and nurses. I probably don't have say much more about that on this board. Patients wouldn't be here if the superlatives turned out to be true.



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