Dr. Smith
3 Replies
Christie - November 2

My doctor says that he can sort of "turbo charge" my eggs by taking the enzyme or protien from a healthy egg and implanting it into my egg. He said it is the substance that is in healthy eggs. Perhaps from the nucleus of a healthy egg. I think it is called Phstoplastic or plasto something transfer.

Do you know of this proceedure?

Please give me your thoughts.



Holly-co - November 2

Not the doc and I am sure he will answer but I think what you are referring to is called cytoplasmic transfer. It is where they take some of the cytoplasm (part of the egg that has energy that powers cell division) from a healthy donor egg and injects that into your egg to help boost energy and hopefully allow your eggs to divide better. St. Barnabas was the only clinic in the US doing it, I believe.

Are you in the US? I am curious as to where you are at b/c their is an indefinate ban by the FDA on this procedure in the US. I would be interested in where this is being offered as I believe it "might" help me as well. I "think" it may have recently been approved in England. One of the reasons it has been banned in the US is because some of the babies born by this procedure (although there aren't a ton) had evidence of dna from 3 parties. Even though the main nuclear dna does not get transfered from the donor egg (that is why this process is appealing, the patient maintains the biological connection) there is some mitochondrial dna in cytoplasm (what is being transferred from the donor) and that was showing up in the offspring. Good luck!


Christie - November 2

Dr. Smith,

Thank you soooooooo much. I have not found any info to research outside of the info you just gave me.

I am in the Czech Republic. We are here for one year. The Dr. said that this may help my eggs to be more complete.

I am 42 and have gone through one IVF cycle in the US. I had 6 eggs from only one ovary. On the third day, I had two 8 cell, two 7 cell, one 6 cell, and one 5 cell embries. The four I had transfered looked to be of good quailty, but, apparently, they lacked something and didn't go all the way.

I an excited to do this proceedure if I can produce eggs again. If not, I will do donor eggs next cycle.




Dr Smith - November 6

Cytoplasmic transfer has been banned for clinical use in the US until its safety and effectiveness can be studied in detail. Although cytoplasmic transfer may hold some promise for women whose problems are caused by defects in the egg cytoplasm (slow cell division, excessive fragmentation, etc), its does not "cure" the genetic abnormalities found in eggs of older women. You simply can't make a genetically abnormal egg "good" again by transferring cytoplasm from a younger egg.



You must log in to reply.

Are you New to the forum? Sign Up Here! Already a member? Please login below.

Forgot your password?
Need Help?  
New to the forum?

Sign Up Here!

Already a member?
Please login below.

Forgot your password?
Need Help?