bicornuate and implantation
1 Replies
WDTP - October 21

Once again, thanks for this invaluable resource, it really is incredibly useful and your honest responses are much appreciated. I have just completed my fourth unsuccessful ivf cycle. In all previous three cycles, I had a transfer on day 2 or 3. This time it was a day 5 transfer of two embryos which were considered to be just on the cusp of blast and the embryologist was very optimistic. They froze another 3 which made it to blast. (Unexplained fertility although post my third cycle I had endometriosis removed from both ovaries – there seemed to be an improvement of egg quality as a result so we had been hopeful, 9 out of 9 fertilised and 5 made it to day 5 ).
My question is two fold:
1.   An ultrasound on my fourth cycle has identified that I have bicornuate uterus, I understand it carries extra risk of miscarriage but does it also impede implantation or does it require a different approach to implantation? How aware of this should my doctor be during the transfer?
2.   The three previous implantations were very quick and no problem, on this fourth cycle, it took almost 30 mins and the Doc had to reload the cathera three times, I didn’t have any pian and it didn’t seem to be a problem at the time but now of course I do wonder if this could have impacted my chances?

Throughout the process my doctor has always been very optimistic and seems to think I have a good chance (a tad ironic but anyway) and I do plan to try again on Number 5 but as much info as possible will certainly help the process.

Many thanks


Dr Smith - November 7

I can't answer the question about how the bicornuate uterus my effect implantation. That's more of medical question.

Day 5 transfers can be troublsome. By then, the cervix has closed off under the influence of 5 days of progesterone. The ease of a Day 3 transfer cannot be compared to a Day 5 transfer - appples and oranges. Repeated attempts at transfer can have a negative effect of the chance of a pregnancy. However, if the transfer did not cause any trauma to the cervix or uterine lining, then its not tht bad and I too, would remain optimistic.

If another cycle is required, the foreknowledge that a Day 5 transfer is going to be a problem, the doc can use techniques to kee the cervical canal open for the transfer.

Best of luck



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