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Topic: Low HCG results (Read 10808 times) |
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AmyR
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well my numbers went down to 21 so after AF I am on to FET. Any ideas on this, I have 14 frozen embryos! What are the success rates fresh vs. frozen? Medicated or not? Thanks Amy
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Dr Smith
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In general, the pregnancy rates for medicated and unmediated cycles is the same. However, medicated cycles make things much more predictable for the patient, physicans and the lab.
The implantation rate for frozen-thawed cell stage embryos (i.e. frozen on Day 3) is about half that of frozen-thawed blastocyst stage embryos. I always recommend thawing Day 3 embryos and culturing the "surviving"embryos to the blastocyst stage (particularly when the patient has several Day 3 frozen embryos). That way you know which embryos have truly "survived" the freeze-thaw process and continued development to the point where they are capable of attachment and implantation (only blastocyst stage embryos can attach to the endometrium and initiate implantation).
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honeybaby
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Hello Dr. Smith,
I guess I am adding myself to the failure list. I posted once a message where I explained that I had 2 embies transfer 1-7 cell and 2-6 cell. Well, we were happy for 5 days when we were told "congratulations" that was on 6/23. 2 days later I began spotting-had my hcg checked and had double to 61.7 and progesterone was 18.7 since then on 6/28 my hcg is at a low of 74.7 and progesterone 23.
My RE's nurse called me with the bad news and told me to stopped with all meds and most likely I will be getting my period and one more thing that if by Friday my hcg is still growing then I would have to take medication to abort.
I saw your post about autoimmune problem and i will be looking into it, but what else could of gone wrong? Never had a miscarriage before and I conceived once a healthy boy naturally ever since my tubes are obstructed and never again pregnat but this second time with IVF. Thanks for your advice.
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Blesed with 1 - 8 yr. old boy; TTC for 7 yrs.
IVF BFP 6/23 early M/C 7/4 :'(
2nd IVF 09/'06 BFP!!! 10/06 baby boy now almost 1 yr. old and 3rd pregnancy on my own
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Dr Smith
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Nothing necessarily went "wrong", but I would suspect embryo quality (e.g. abnormal genetics). It is impossible to say for sure, but abnormal blastocyst stage embryos having very few stem cells produce "chemical" pregnancies such as yours. Chemical pregnancies are common, even amongst the "fertile" population. It is nature's way of terminating the abnormal pregnancy as early as possible, so that you can try again on the next cycle. It is natural to search for answers following a chemical pregnancy, but it may be just part of the natural process of reproduction.
That being said, I agree that you should be checked out for evelvated NK cells and/or abnormal NK cell activation (just to be on the safe side).
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honeybaby
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Thank you for your words Dr. Smith, and thanks to this web, I am educating myself alot.
Trust me I am going in to my dr., asking all sorts of explanations, of course I am not blaming any one and most take what God chooses best for me.
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Blesed with 1 - 8 yr. old boy; TTC for 7 yrs.
IVF BFP 6/23 early M/C 7/4 :'(
2nd IVF 09/'06 BFP!!! 10/06 baby boy now almost 1 yr. old and 3rd pregnancy on my own
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AmyR
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Hi there remember me?? My numbers went from 23 to 42 to 21 then I stopped prog and estrogen and got AF. Numbers then up to 28, and 4 days later up to 58, and they now want me to come in for US next wed. What is going on and what do they suspect? any ideas... ectopic? I really don't know what to think.
On another note... what do you think about acupuncture? thanks Amy
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Dr Smith
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The may suspect an ectopic, hence the ultrasound.
There have been some recent journal articles regarding the potential benefit of acupunture as an adjunct therapy to ART, but I personally remain skeptical. The studies were on relatively small numbers of patients and the mechanism of action (from a western medicine point of view) remains unclear. There is no shortage of patients singing the praises of acupunture on the net, but their successful cycle following acupunture could have be attributed to a multitude of factors. I'd say the jury is still out.
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AmyR
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Thanks so much for your helpful advice. I look forward to your knowledge when I ask questions. Amy
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gap5406
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just hanging in there...
day 8 beta: 26, day 10 beta: 44, day 13 beta 73. my dr. wants me to keep going and get re-checked in a week.
oh and i had pgd...and two good embryos transferred...so genetically they are supposed to be healthy.
anyone have any insights?
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