I wrote you last week "1st IVF". Thank you for your response (40-50% chance of viable pregnancy). Found out yesterday that it was a chemical pregnancy ( sooooo sad). Beta 9dp5dt with two blasts was 24 and two days later it went to 10. I am told by my clinic that they froze 3 "good" blasts on day six. I am moving forward with a FET after a natural cycle. My questions are what are the odds of these blasts surviving the thaw and my chances of conception. Feeling a bit hopeless today after coming so close.
Also, they said they don't do assisted hatching on blasts. They said it is damaging to the blast although I see that you do this and must assume they just are not confident with their ability to do this successfully. Since I had a chemical pregnancy would it then be safe to assume that my future FET could be successful without AH? Thank you for all your time and expertise.
Take heart! Your chances are good (about 50/50) with an FET of 3 thawed blastocysts. Unlike Day 3 cell stage embryos, blastocyst stage embryos survived freezing and thawing very well. Hang in there.
The protocol I use for hatching blastocyst stage embryos does not harm the embryo. In our center, we have seen a significant increase in blastocyst implantation rate following assisted hatching. The hatching protocol was published in the following scientific paper:
Sagoskin AW, et a. (2002) Healthy twin delivery after day 7 blastocyst transfer coupled with assisted hatching. Fertil Steril. 77:615-7.
You may forward this information to the embryologist at your clinic. They can contact me if they have any questions.
Dr. Smith, Thank you for your answer. As far as hatching I am reluctant to let my blasts be the first they try the new protocol on. If they don't do you think I still have a 50/50 chance given that I have already had a chemical pregnancy thus at least one of my blasts have implanted in the last cycle?
Yeah, I know what you mean. Nobody wants to be a Guinea Pig. I'd still say 50/50, if all embryos survive the thaw (and they should) and all three embryos are transferred.
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