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Topic: FET (Read 837 times) |
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saverb
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Dr Barry,
I had two unsuccessful IVF's (ISCI) before and today I'm due for the frozen transfer.
The first time I used the oil for my progesterone and I had a really bad reaction (I could not walk, seat, lay on my back). The second time my doctor told me to use the Prometrium and it worked well. So this time for my FET I've been taking Prometrium again.
Yesturday my BW showed that I have low progesterone levels (5.09) and the nurse told me to increase my dose of Prometrium. Today when I called the office to get my instructions for today they told me that I should switch back to using the oil (my doctor is on vacation and it was another doctors instruction). They also told me that they are not going to reschedule the procedure because my lining looks ready.
My questions are: How will low progesterone levels effect my chance on getting pregnant with FET (I was also very stressed out through the night because I could not get any answers form the nurse)? Does it make sense that Prometrium was good for me during the last cycle and not this one? The Prometrium that I was using is from my previous cycle. Could it expire or become less effective even though the exp. date on the bottle is in October, 2005? Any other thoughts would be greatly appreciated.
Thanks in advance for you response.
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saverb
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Forgot to add that the Prometrium that I was using is from my previous cycle. Could it expire or become less effective even though the exp. date on the bottle is October, 2005?
Thanks!
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Barry Jacobs, M. D.
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I do not know the oil you had used previously. Many women have reactions to peanut oil. That is why I prescribe progesterone in sesame oil. Oral progesterone is vey unreliable. I do not use it. I use a combination of injection and vaginal progesterone. Fro any delivery method other than vaginal, you need a serum progesterone level of at least 20 ng/ml to achieve and maintain a pregnancy.
Good luck.
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saverb
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Thanks you for your reply.
I went through my frozen transfer with Progesterone at 5.09 the day before. I was told to start oil progesterone again. I used sesame oil during my first cycle and this time I'm using olive oil. I have a really bad reaction to this one too (high temperature, around 101) but I was told to use it anyway because there is no other way to keep my progesterone levels up. On the second day after the transfer my prgesterone was only at 15.7, so they increased it from 1cc to 2cc. Do you think I still have a chance of getting pregnant with my progesterone being so low in the begining and that I use tylenol to keep my temperature down.
Thanks
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Barry Jacobs,M. D.
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Progesterone is one of the hormones necessary to maintain the new pregnancy. It should be present in a concentration of 20 ng/ml, to establish and maintain your pregnancy. I do not use Prometrium, because the blood levels of orally administered progesterone are extremely unreliable. I have my patients use progesterone in sesame oil (not peanut oil) injections, and progesterone vaginal capsules.
Good luck.
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tschus
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We just had our first IVF March 2 which failed. We had 10 embryos, 2 were used for IVF#1, 6 didn't make it to freezing so we now have 2 left that are frozen. We're planning on doing an FET sometime in May. Our RE said we could schedule it anytime after my cycle, but I'm wondering isn't there a "best" time or does it really not matter??
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36 yrs old. DH 33 yrs. old. Married 8/11/01, TTC since then. 2 dogs, no children. IVF#1 4/2/04 - BFN. FET possibly in May.
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Barry Jacobs, M. D.
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FET needs to be done after the endometrium is stimulated to be greater than 7 mm thick, and then, treated with progesterone for 1 week. This endometrial preparation can take place in a normal ovulatory cycle.
Good luck.
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