Stimulation Medications & Impact On Egg Quality
1 Replies
dmracek - February 26

Dear Dr. Jacobs,

I recently went through my first IVF cycle unsuccessfully and hope to do another cycle. I am 41 years old, my FSH is 13.1 and E2 is 85. Just 11 months prior it was 10.1 and 50 (wow, what a year will do!).

I was on the Micro Dose Lupron Flare protocol. I started with BCP, then took 40 units of Microdose Lupron for 17 days, 450 IU Bravelle/150 IU Menopur for 15 days and then the HCG trigger shot. We started with 8 follicles that grew to 10, we retrieved 7 eggs, 5 mature, 5 fertilized. Of the 5 embryos only one made it to the blast stage at day 5. I believe the average number of stimulation days is 11, is that right? My question is can the extra 4 days or so of stimulation medications compromise the egg quality. If so, could there be a better (or different) protocol for me to try in round 2?

Regards,
Donna

 

B. Jacobs, M. D. - February 26

WE typically give hCG on cycle day 12 and retrieval on cycle day 14. Please remember that after the age of 40, egg quality declines dramatically.
Good luck.

 

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