Morphology?
1 Replies
Nix - February 1

Dear Dr. Jacobs,

When we started this process, we were told that my husband's morphology is 6%. Is this good or bad? What is a "normal" number for morphology?

Thanks
Nikki

 

B. Jacobs, M. D. - February 1

There is not a single standard set of criteria for spem morphology. Many labs do not use any published set of criteria, at all, for determining morphology. A lab tech glances at the sperm as they swim by and guesases the percent normal forms. Usulally the report is 90%, when that is done. The WHO modified their estimate of normal. Previously, they poled urologists asking what percentage of normal forms should be in the ejaculate. The number established was 80% or more. In each case, there is no correlation with sperm function.

In the 1980's Thenius Kruger established what he called a set of strict morpholgy determinants for sperm. He yhen correlated his scoring system with the ability of sperm to fertilize mature eggs in the IVF lab. Kruger publish a great many reports of his scientific investigations, all indicating that if 10% to 14% were normal, by his strict criteria, there was virtually 100% fertilization of mature eggs, and that all aspects of sperm function were apprpriate.

Taht was a bit of a long discussion to say that I do not know what criteria were used to evaluate your husband's sperm. If Kruger's strict criteria were used, he may not be in bad shape, and intrauterine insemination, after your ovaries are stmulated with an FSH product may be a reasonable treatment protocol.
Good luck.

 

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