hydoxyprogesterone and hormone levels
3 Replies
MAg - November 7

Dr. Jacobs....

I have the printout of my lab work from my doctor. The results are as follows:

DHEA SULFATE 117 MCG/DL

FSH 5.5 MIU/ML

HYDOROXYPROGESTERONE, 17- 32 NG/DL
ALPHA-

LH 16.3 MIU/ML

PROLACTIN 9.5 NG/ML

TESTOSTERONE, TOTAL 72 NG/DL

TSH 0.90 MIU/L

ESTRADIOL 75 PG/ML


I know I have PCOS, so my LH to FSH ration is 3:1, but is hydroxyprogesterone mean my progesterone level? Is it okay?

Thanks so much!


 

Barry Jacobs, M> D. - November 7

The pre-hormone, 17-hydroxyprogesterone, is in the pathway to make cortisol. Adeficiency of an adrenal hormone, 21-hydroxylase, causes an elevation of 17-hydroxyprogesterone, which is then shunted into the pathway to make male hormones. Deficiency of 21-hydoxylase is the most common single gene defect we know, and causes a condition which looks like polycystic ovaries. A far more common cause of polycystic ovaries is insulin resistance.
Good luck.

 

MAg - November 8

Are my levels normal or do you suspect a gene defect?

 

Barry Jacobs, M. D. - November 8

You are OK.

 

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