FSH and Estradiol
3 Replies
meridithhasfaith - May 8

Hi Dr. Jacobs,

Could you please comment on what the outlook for ovarian response would be in a healthy 36 yr old woman with an FSH of 6.94 and estradiol of 125 at cd3? I should add that I also had a sonohystogram on cycle day 8 of that same bloodwork cycle and was told I was about to ovulate. Could being earlier in the follicular phase than we thought cause the elevated E2 and not necessarily a poor prognosis for ovarian response?

Thank you,
Meridith

 

Barry Jacobs, M. D. - May 8

An FSH of 7 Iu/L is fine, but on cycle day 3, an estradiol of 125 pg/ml is high. It may falsely suppress FSH. Probably a more accurate estimate of ovarian reserve can be made by counting the number of follicles visible on ultrasound on day 3.
Good luck.

 

meridithhasfaith - May 9

Just a quick follow-up. Do you think that being further along in the follicular phase when the blood was drawn could cause the E2 to be high?

Thank you,
Meridith

 

Barry Jacobs, M. D. - May 9

Yes, your estradiol level is lowest on cycle day 3, and rises to a peak a day before ovulation.

 

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