Need urgent advice re: Lovenox/Baby Aspirin in case of APC Resistance
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Faith710 - February 2

Hello Ladies:
I have learned a lot by scanning the boards but unfortunately I am still confused and am seeking advice. Let me give some history...

I am currently 18w pregnant with twins. I had two miscarriages last year after IVF procedures - one @ 6 weeks due to unknown cause and the other @ 7 weeks due to chromosomal abnormality. Due to the chromosomal abnormality finding, we added PGD testing to the mix and transferred two normal embryos in October. I was also placed on lovenox, baby aspirin and hi-dose folic acid (folgard) by a hematologist due to the following findings:

Borderline APC Resistance (Negative for Factor V Leiden)
Postive for One Copy of the C677T Mutation (MTHFR)

In mid November, I was rushed to the ER for severe bleeding and it was discovered that I had a subchorionic hematoma. My peri took me off the lovenox and baby asprin right away and sent me home for bedrest until the hematoma resolved.

6-7 weeks later it was gone. Now the hematologist wants me to resume lovenox and baby asprin (I stayed on folgard since there was no risk) and my peri said no - will only concede to baby aspirin and even feels that is unecessary.

So, there is my dilemma...In the absence of Factor V Leiden and only a borderline test result for APC resistance, are the injections and baby aspirin necessary???

Since things have been progressing so well I'm scared to rock the boat.

Any advice/insight would be greatly appreciated.

Many thanks,
Faith

 

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