Slow growing embryos. Bad genetics?
0 Replies
Alchik - June 4

Hello,
I have recently gone through 2 Fresh IVFs.
Both times I was on the short protocol due to Factor V Leiden and not being bale to take BCPs for the long protocol.
[u][b]1st IVF April 2008[/b][/u]
E2 was 5026 1 day after trigger 1 day before ER (the cancelled the ET)
22 Eggs retrieved
18 fertilized with ICSI
11 fertilized
3 had triplody
8 were frozen at 2PN

[u][b]2nd IVF May 2008[/b][/u]
E2 was 2700 day after trigger 1 day before ER
20 Eggs retrieved
15 fertilized with ICSI
8 fertilized

The 8 that were frozen were thawed to mix in with the fresh batch.

Day 2 Stats:
From fresh cycle: 7 were still progressing (2 and 4 cells)
From frozen cycle: 5 were still progressing (2 and 4 cells)

Day 3 Stats:
From fresh cycle: 4 4-cells and 1 5-cell = 5 still progressing
From frozen cycle: 2 4-cells and 1 5-cell = 3 still progressing

Day 4 Stats:
From fresh cycle: 1 8-cells and 1 6 cells = 2 still progressing
From frozen cycle: 1 8-cells = 1 still progressing

Day 5 Transfer
From fresh cycle: 2 morulaes ( ok quality )
From frozen cycle: 1 blastocyst (poor quality)

Both my husband and I are 30 years old (just turned in March)
By looking at these results what do you think? Do you think we have a egg or a sperm issue?
Do you think that we should try for IVF #3 or is there no hope to get PG with our own genes.
To let you know of my prior history, I had a blighted ovum miscarriage 5 years ago with a different partner (DnE done, no genetic testing done). Last Sept (07) I became PG through an IUI and injectables, HB was good, but at 11 weeks there was no HB and had a DnE done. Baby had Trisomy 21.
Both my husband and I were tested for karyotyping and we're both OK, no translocations.

So I guess, I'm asking you if you think I should still be hopeful and do another IVF. My current clinic is very busy, they do over 1000 transfers a year, so their embryology lab is pretty good, so I don't think this could have been a lab error.

I'm desperate to know what your opinion is. And I'm ready for a bruitally honest answer.

Thanks So very much in advance!

 

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