Slow growers
1 Replies
JaneX - June 19

On our first round of ISCI we did a 3 day transfer with 3 good grade embryos but 2 only had 4 cells and 1 had 5 cells. It resulted in a positive pregnancy and we have a healthy little boy. On our second round 17 months after the first round we got the same outcome with the embryos and transfered 4 - 1 at 5 cell and 3 at 4 cell but got a -ve.

All our embryos have been slow growing. On the first cycle nothing made it to 5 days. On the second cycle they froze 6 at 3 days but all 4 cells. They said they didn't think they would make it to 5 days. Aside from the number of cells everything else looks perfect.

Is there anything you can do about these slow growing embryo's? What is most likely to be the problem - egg, sperm or a mix of both?

Thanks for your help.
Jane

 

Dr Smith - June 22

The sperm's contribution to the embryo development does not kick in until Day 3, so any abnormalities observed prior to Day 3 are a result of egg "quality". There is no easy answer for your situation. If the stimulation was of adequate length (i.e. minimum of 9 days), then the eggs had adequate time to undergo maturation in the follicles prior to retrieval (a short stimulation can result in immature egg cytoplasm and cause slow development). I can't think of anything else that results in slow, but otherwise good quality embryos. The only other explanation is that's just the way your eggs are and nothing can change that.

 

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