Round Cells
3 Replies
tatty - August 6

Hi Dr Smith,

My partners semen analysis always shows a high round cell count, his last one showed 15 million/ml round cells. Count was 13 million/ml.

His hormone levels have come back normal and he has been treated with antibiotics twice, once with doxycycline but still they remain high.

Should we be worried about this ?, will the high round cell level be affecting count/morphology/motility ? The analysis mentions peroxidase positive.

Any advice would be appreciated.

Regards,

Tatty

 

Dr Smith - August 8

Sometimes, UTI's in men can be difficult to treat and resistant to antibiotics. The high concentration of white blood cells (a.k.a. round cells) can adversely affect sperm function. In these cases, IVF/ICSI is the usual treatment because the "good" sperm can be isolated and injected directly into the egg. This overcomes the potential negative effect of the high WBC's.

Peroxidase staining is a method of differentiating WBC's from other "round" cell in the ejaculate. Peroxidase positive means the round cells were positively identified as WBC's.

 

tatty - August 13

Hi Dr Smith,

Is there no other course of action/treatment to reduce these WBC's? e.g try different antobiotics?

Many thanks,

Tatty

 

Dr Smith - August 14

UTI's in men as difficult to treat, as they are often resistant to a variety of antibiotics. After about three different antibiotics, most docs give up. Men with UTI's are often asymptomatic. They never know they have one until they have a semen analysis. If you are trying to conceive naturally, this is probaably a contributing factor to your infertility. If you are doing IVF/ICSI, it doesn't really matter.

 

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