PGD or not?
0 Replies
jtc1973 - April 6

Dear Dr. Tim,

I'm a 37-year-old, and last year I gave birth to a trisomy 13 baby who was born 10 weeks early. It was a big shock for everyone. Though I didn't do an amnio, nothing on the ultrasound scans indicated trisomy 13 (i.e., no heart defect, etc.).

We're getting ready for another round of IVF and my doctor has suggested that I do PGD, or PGS. From what I've read on the Internet, there seems to be a lot of controversy over PGD and whether or not it improves implantation and live birth rates.

We had our first IVF in 2009, a fresh transfer, which resulted in a negative test. I've also had three failed FET's: one controlled cycle, two natural cycles. In the first stimulation cycle, I had 19 eggs, 11 of which fertilized and were day 3 embryos. There were about three good quality ones. But during that cycle, I was overstimulated, which I think resulted in poor quality embryos.

The most recent stimulation round in 2010 produced 9 mature eggs, six of which made it to day 5 blastocysts: two were graded 5AA, one 4AA, two 4AB, and one 4BB. We transferred three, which resulted in a twin pregnancy. One disappeared at 8 weeks, and the other was our trisomy 13 baby.

Given my history, would IVF with PGD be advisable? Either way, I will definitely do an amnio if I became pregnant again.

Many thanks.

 

Message:


You must log in to reply.

Are you New to the forum? Sign Up Here! Already a member? Please login below.




Forgot your password?
Need Help?  
New to the forum?

Sign Up Here!


Already a member?
Please login below.





Forgot your password?
Need Help?  
Ask a Question