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sblanton2 - August 25th, 2005 1:51 PM

Sir,
Sorry to bother you but I have one more question(for now...LOL). I apologize if you have already answered this.
Is there an increased risk of identical twins when ICSI is performed in comparison with regular IVF? I was just wondering if the additional munipulation of the egg caused it to split?
Thank you for your patience.

V/R,
Sylvia

Dr Smith - August 25th, 2005 1:59 PM

I am not aware of any reports suggesting a higher identical twinning rate following ICSI. This is probably because the hole made by the sperm injection needle as it passes through the zona is very small (3-5 micrometers) in comparison to the egg (120 micrometers in diameter). And, surprisingly, the manipulation of the cytoplasm during the injection procedure does not appear to have a detrimental effect on embryo develoment either.

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