Grade A day 3 embryos didn't make it to blastocyst
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rpatel010 - October 9

Hello Dr. Smith,
I am a regular reader of this forum. Just wanted your expert advice on my case. Here are the details.
I had two IVF cycles so far because of unexplained infertility. My husband's sperm analysis look normal. My both IVF cycles failed. In first cycle, only 5 eggs were retrieved. All fertilized, transferred 3 of them since doctor thought they were not of good quality embryo on day 1, transferred 3 on day 2.

2nd cycle: Was good cycle as far as stimulation goes. Retrieved 16 eggs. 13 fertilized. Looked good on day 1, so doctor said he will wait until day 5 and transfer only one blastocyst. We were happy. Out of 13, 10 embryos were A quality on day 3 with 6-12 cells each. When we were at the clinic on day 5 morning, doctor said he didn't have any blastocysts, not even morulas. All but only 2 embryos were arrested. The two were at the pre-morula stage. and were hatched and then transferred. We knew that chances were zero.

What could have gone wrong? If 10 A grade embryos were available on day 3, why no blastocysts on day 5? Doctor himself was surprised and said never seen that in his lifetime. I just need your expert advice on this. What should we do in our next cycle? Do you think all of our next cycle embryos will also get arrested before making it to the blastocysts?

Thanks for your time.

Raj

 

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