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justme - August 30th, 2005 4:34 PM

What success rate would you give 4-cell embryos that are transferred on day three? They were described as fragmented.

Thank you


justme - August 30th, 2005 5:40 PM

Also, they were scored a 5 on a 1-5 scale.

Thanks


Dr Smith - August 31st, 2005 8:20 AM

In terms of cell number, it difficult to predict the developmental potential of these embryos because they had not yet progressed to the 8-cell stage (which they should have done by Day 3). Many genetically abnormal embryos stop growing between the 4 and 8-cell stage.

Different laboratories use different rating scales. For some laboratories a "1" is the best grade, for others a "5" is the best grade. However, since your were told that the embryos exhibited fragmentation, and a "best grade" embryo would have no fragmentation, I will assume that the Grade 5 you refer too is the worse grade on this laboratory's grading scale. If this is true, your chances of success are very low.


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