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Hi Emily :)
I have had 3 IUI's with Clomid and Ovidrel. I have never used Estradiol, so I'm not sure how that affects the way you're feeling. I know for me, I would feel pretty out of sorts up until the Ovidrel shot. Sometimes after the shot, I'd feel restless or have trouble sleeping. As soon as I ovulated though, I'd start feeling much better. When I ovulate from an Ovidrel shot, it's a much more intense feeling. I actually feel my ovary spasm, so don't be suprised if ovulation feels a little different than normal. I wish you the best of luck!
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