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Red7 - April 16th, 2009 6:50 PM

HI DR Jacobs, What is the difference between Clomid verses Nolvadex ? They are both anti estrogens right? I never get pregnant on Clomid , And never got pregnant off of Femara , But I did get pregnant off of Nolvadex, But had chemical pregnancy, Why did Nolvadex work on me but the other two didn't.Thank You

B. Jacobs, M. D. - April 17th, 2009 6:37 AM

I am not familiar with Nolvadex, by that name, and have not looked it up, yet. I am sorry that I do not have an answer to your question, at this time.

Red7 - April 17th, 2009 8:05 PM

Hi Doctor Jacobs,Nolvadex ( Tamoxifen)is a Anti-estrogen drug.After you have Looked it up. Than can you answer my question. Thank You

B. Jacobs, M. D. - April 18th, 2009 7:59 AM

Tamoxen and clomipen (Clomid) are related compounds with similar mechanisms of action. There are likely to be subtle differences in the way they modify the response of the estrogen receptor. I have not read a detailed description of these differences, but I can tell you that they both block the estrogen receptor, and at the same time have some limited stimulatory effect.

Red7 - April 18th, 2009 5:41 PM

Thank you Doctor Jacobs for answering my Question.

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