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dmracek - February 28th, 2009 10:49 AM

How reliable is PGD. I've heard there can be false positives with this test. Is that true?


B. Jacobs, M. D. - February 28th, 2009 3:52 PM

That depends on why you are having PGD. Ifyou are looking at chromosomes, the way it is currently being performed looks for specific sites on 7 different chromosomes. If you are trying to detct an inhertited disease carried by parents, it is test of DNA. The latter is far more sensitve and acurate. There is a new technology to be introduced soon which will be far better at detecting an abnormal number of chromosomes, but requires doing a biopsy of a blastocyst and then freezing the embryo for transfer later.


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