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saverb - March 28th, 2005 8:58 AM

Dr Barry,

I had two unsuccessful IVF's (ISCI) before and today I'm due for the frozen transfer.

The first time I used the oil for my progesterone and I had a really bad reaction (I could not walk, seat, lay on my back). The second time my doctor told me to use the Prometrium and it worked well. So this time for my FET I've been taking Prometrium again.

Yesturday my BW showed that I have low progesterone levels (5.09) and the nurse told me to increase my dose of Prometrium. Today when I called the office to get my instructions for today they told me that I should switch back to using the oil (my doctor is on vacation and it was another doctors instruction). They also told me that they are not going to reschedule the procedure because my lining looks ready.

My questions are: How will low progesterone levels effect my chance on getting pregnant with FET (I was also very stressed out through the night because I could not get any answers form the nurse)? Does it make sense that Prometrium was good for me during the last cycle and not this one? The Prometrium that I was using is from my previous cycle. Could it expire or become less effective even though the exp. date on the bottle is in October, 2005? Any other thoughts would be greatly appreciated.


Thanks in advance for you response.


tschus - April 5th, 2005 9:37 PM

We just had our first IVF March 2 which failed. We had 10 embryos, 2 were used for IVF#1, 6 didn't make it to freezing so we now have 2 left that are frozen. We're planning on doing an FET sometime in May. Our RE said we could schedule it anytime after my cycle, but I'm wondering isn't there a "best" time or does it really not matter??


Barry Jacobs, M. D. - April 6th, 2005 6:39 AM

FET needs to be done after the endometrium is stimulated to be greater than 7 mm thick, and then, treated with progesterone for 1 week. This endometrial preparation can take place in a normal ovulatory cycle.
Good luck.


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