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nina - April 7th, 2005 5:25 PM

Hello DR, I had a question about the E2 levels. My E2 level are 2400 @ day 7 of stims and I have around 24/26 follicles. I am concerned about the E2 level rising high and having bad egg quality! But, my RE finds my E2 level perfect. I am supposed to trigger on satureday.

Last IVF I had my E2 levels at 3200@trigger day and I had bad egg quality. Had 20 follicles last time and only 5 good quality eggs out of 10 retrived.

I was wondering if anybody had such E2 level and had good egg quality.

Thanks.
Nina

Barry Jacobs, M. D. - April 7th, 2005 7:12 PM

The issue we see is dysynchronos maturation of egg nucleus and cytoplasm if estradiol levels rise too fast. With levels over 3000 pg/ml, you are also at greater risk for a hyperstimulation syndrome.
Good luck.

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