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doglover - October 12th, 2007 9:44 PM

Hi Dr. Jacobs-
I am part of an IVF drug study at my clinic, and this is my first time using Crinone 8% gel. We are using it only one time daily, starting the day after retrieval. Everyone has a day three transfer with a follow up progesterone level three days after the transfer. What range is normal? I read somewhere that it tends to concentrate so well in the uterus that it can commonly lead to low serum levels.

Thanks,
Lindsay

B. Jacobs, M. D. - October 13th, 2007 8:11 AM

Actually, vaginal administration of progesterone is not likely to produce a high serum level of the hormone. It does produce a good tissue level in the endometrium, where you want it. I cannot tell you what level to expect in your blood.
Good luck.

doglover - October 13th, 2007 12:42 PM

Should I be encouraged if my progesterone level was 130?
Thanks,
Lindsay

B. Jacobs, M. D. - October 13th, 2007 4:05 PM

Anything over 20 ng/ml is fine.

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