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Lovenox and pregnancy

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chynnadoll - Feb 9th, 2006 11:20 PM
[Original Post]

Has anyone taken Lovenox through out there pregnancy and delivered and healthy full term baby? I have had several m/cs and this is my first pregnancy on Lovenox.

Anyone with some information will be helpful.

Thanks...China, Baby dust to all


Jeneca - Feb 23rd, 2006 3:48 PM

Yes, I had my son that way. I suffered through 3 miscarriages before my new doctor decided to put me on lovenox. Started taking it at about 5-6 wks along and stopped it at 36 wks. My son was born at 39 wks. Had a very normal pregnacy and son was/is very healthy. He is 3 yrs old now!


Audrey - Feb 28th, 2006 6:54 PM

I am pregnant for the first time, and on Lovenox for Factor V. My Ob prescribed 40mL once a day, then my Hematologist upped it to twice a day. Is this normal, and will it increase the risks?


chynnadoll - Mar 1st, 2006 1:06 AM

Audrey,

I'm on Lovenox also, I have been on it since Oct 05, I am on 60mg once aday, My Ob Dr told me once pregnant they would increase the dose.

I just miscarried 2-3 weeks ago, and they did'nt get a chance to increase the dose, I think it will only help with your pregnancy, There is know harm in taking Lovenox while pregnant.

I would rather have enough then not enough!

I have an apt for the first time with a Hematologist, how did your apt go? and exactly what was done? I just figure it will be alot of blood work, do you feel the visit was helpful?

Good luck to you through out your pregnancy, keep us updated! :) You will be in my prayers...Take Care, China


HeatherMac - Mar 23rd, 2006 9:59 PM


China,

I delivered a healthy baby 11/05, and I was on Lovenox from the day I got the confirmation beta until six weeks AFTER he was born. Apparently, with clotting problems, the greatest risk of throwing a clot is AFTER the baby is born...so I was on Lovenox for nearly 11 months.

I suffered from m/cs before the pg, so my RE put me on 30mg 2x/day right away. However, after I finished the course of treatment, my OB asked why I didn't do the 60mg shot instead of the two 30mg shots I did. Grr. Anyway, I have TONS of clotting factors and issues that I can't even remember - Factor XI was one I remember, and there are several more I just can't remember. I thought it was MTHFR, and Factor V, but it's neither of those.

I was also on 5mg of Folic Acid per day PLUS two Foltx tablets to help wtih the clotting. All the folic acid and b vitamins keep the blood less from getting sticky, so with the Lovenox and the extra meds, AND the grace of God, I had a wonderful miracle.

You might want to ask about the folic acid and foltx...it's a lot of extra pills per day, but worth it for peace of mind.

I hope they get your meds straight so you can have a happy, healthy pregnancy and get that precious bundle in your arms!!

Best wishes and baby dust to you!


HeatherMac


Heidi - Apr 12th, 2006 9:02 AM

Thanks for the posts. I am starting Lovenax today and a little freaked out but going by what my docs say. I am 6w3d and hope to hold onto this one. Thanks again



aprila - Apr 18th, 2006 2:21 PM

I am 6week and 2days, I have had three miscarriges before i found out i had a blood clotting disorder the doctor started me on lovenox yesterday. the shot was really painful it burned really bad is this normal? I wish all of you good luck.


HeatherMac - Apr 18th, 2006 11:39 PM


Aprila -

Yes, the Lovenox burns going in...and it doesn't get much better, I'm sorry to say. I was on it for ten months in total, but I was grateful to have it.

I found that a little ice rubdown of the injection site helps with the burn.

Good luck to you ladies!!


HeatherMac


Susan - Apr 22nd, 2006 9:33 PM

Hello -

I just came across this thread and am so glad that I did. I am 10 weeks pregnant and started taking Lovenox 2 days ago (1 injection a day -- 40 mg). I am also taking a daily baby aspirin and folic acid. For the first time, I had some bleeding today and am very worried.

My question is if anyone has experienced any light bleeding while on Lovenox? Of course I am worried about a m/c but I am also hoping that it might have something to do with starting the injections and baby aspirin?

Any information would be greatly appreciated.
Thank you,
-Susan


HeatherMac - Apr 22nd, 2006 10:22 PM


Susan,

Why are you on asprin while you're on the Lovenox?? If your doctor put you on it, I'd ask why you're on it. I was told I could not even be taking asprin while taking Lovenox...it's a blood thinner, and so is the asprin, so that may be part of your bleeding.

Just ask your doc when you talk to them again.

Let me know what happens!!


HeatherMac


Tiffany F. - Apr 23rd, 2006 12:06 AM

Hey Susan,

I was also on Lovenox, 81mg of aspirin, folic acid and pre natal pills I m/c at 7 weeks.

I pray that's not your case, sometimes we do experience light bleeding during the first trimester, I don't believe there is anything wrong with taking aspirin and Lovenox or Heparin, I am on Heparin now still trying to conceive as well as aspirin and the other things I mentioned above.

Lovenox and Heparin are both blood thinners, and if your Dr put you on them both it must be necessary, it's all depending on what kind of clotting disorder you have.

Just to be safe I would probably go to the emergency to make sure everything is OK.

Have you had a m/c before? I pray everything is OK, please keep us posted on your situation, Just pray and believe all goes well!

Take Care....Tiffany


Susan - Apr 23rd, 2006 8:36 AM

Thank you both so much for your responses. I was so relieved to see your messages this morning and so appreciate the support and information.

I have never had a m/c before (I have a 2.5 year old daughter -- delivered by emergency c-section due to placenta abruption). I did go yesterday to my drs. "after-hours- care" so while I didn't see my ob/gyn I did see a dr. She checked my cervix and told me it was closed. Is that a good sign against a m/c? I just am so anxious until Mon. when I can see my ob/gyn. The bleeding continues but not in a steady way. Overnight I did pass a small blood clot. I don't understand this given that I am on blood thinners?

It was a perinatologist that put me on both the 40 mg. Lovenox injection and a baby aspirin. She also said I should continue taking folic acid, my prenatal vitamin and a calcium supplement. I met with her last Wed. per my ob/gyn's referral (it will by my ob/gyn who I will interact with regularly). I tested positive for both MTHFR and APS. My numbers are in the mid-range (not the highest but not the lowest).

I have to thank you again for being there for me! Just being able to talk about it with women who understand helps so much.

-Susan


Tiffany F. - Apr 23rd, 2006 5:46 PM

Hey Susan,

You are so wlcome, you have come to the right place for support, women here have been through what you are going through, you can always find someone to relate to.

Your cervix being closed is excellent, but usually I believe you don't have to be real concerned about that early in the pregnancy, m/cs that usually happen in the first trimester we have know control over, I have had six, and I just feel that something was wrong with the baby and it was'nt meant to be here and to suffer.

That's just my thoughts.

And with you passing the small clot, that does'nt mean that you had a m/c, you need to get a beta count down and then get another in 48 hours and that will put your mind at ease.

I was told by my Ob I had APS, but when I saw the Hematologist he said the test for that and everything else was negative.

I pray all is well with you, please keep use posted, while you are bleeding or spotting try not to do any heavy lifting and get as much rest as possible with your feet elavated.

Take Care....Tiffany


HeatherMac - Apr 23rd, 2006 7:45 PM


Susan,

Tiffany is right - much more to clotting than I am aware of...I just find it so strange that I was told NO asprin. Tiffany tells you right - so stick with her knowledge and experience.

I hope both of you are well and I will keep you both in my prayers.


HeatherMac


TanyaT - Apr 24th, 2006 9:55 AM

[b][/b]Susan,
I am 7 wks today and started Lovenox 40mg injections on 4 days ago. The same day I started, I bled a little and went to the ER just to be safe. I ahve lost 2 pregnancies in 9 months so I am a little paranoid! They did complete bloodwork and an internal ultrasound and found the baby was just fine. I think the Lovenox had something to do with the bleeding, YES. I have been diagnosed with Anticardiolypin blood clotting disorder and hope the Lovenox helps us keep this baby. I really DON'T think you are supposed to still be taking the baby aspirin! My specialist told me to stop the day before I started the Lovenox. I would call your Doctor immediately and clear this up. Remember, you can't be too paranoid, call 100 times if you need to! I hope this helps.
TanyaT


Susan - Apr 24th, 2006 11:17 PM

Hello -

All of your responses have helped me so much -- thank you.

I finally was able to see my ob/gyn's office today and they did a vag. ultrasound. Thank goodness the baby's heartbeat was there! It had been such a long weekend and the bleeding did not ease off until today. (unfortunately the way my health insurance -- Kaiser Permanente HMO -- is set up, for weekend medical attention one goes to these medical centers where they do not have an ob/gyn on call or an ultrasound to ease one's mind -- it is so frustrating)

My ob/gyn today said that the bleeding (which has almost stopped - thank goodness again) did not seem to be related to the baby. He thought the bleeding might be due to a possible capillary or the like that I have that is close to the surface. He thought that the blood thinners I am on (the daily baby aspirin and lovenox) could be causing it to bleed. Of course he can not be positive.

Both my ob/gyn from today and another in the practice did seem surprised that the perinatologist I met with put me on both baby aspirin and lovenox. I thought that was interesting. But then they both separately stated that she (the perinatologist) was the specialist and deferred to her stating that I should continue as she prescribed. I am not sure what to make of all that?

Anyway, I can not even begin to express to all of you how much you helped me this weekend. It was such a scary two days and your helpful and kind messages meant so much. Please know that I will keep all of you in my prayers for only the best of outcomes.

-Susan


Aprilsteph - Apr 27th, 2006 11:13 AM

Hi Heathermac.
Thanks for the info. I pregnant with my 3rd baby, and just found out i have factor 5. I started my lovenox yesterday, and I am on 70 Mg 2 x day. I thought that was kind of much considering my size. But I guess we will have to see. My first preg went good, but with 2nd my son was 8 weeks early due to clotting in placenta. I am currently 18 weeks and praying alot!
But it is good to hear you and your baby are well and it is a success story.
Much love, April


Stacey Korba - May 1st, 2006 12:40 PM

I also had a little bleeding. It was only a little bit red and then would be brown discharge for days. My doc took me off the asprin and said just take the lovenox. Well I haven't bleed since.


[quote author=Susan link=board=13;threadid=1981;start=0#17513 date=1145756018]
Hello -

I just came across this thread and am so glad that I did. I am 10 weeks pregnant and started taking Lovenox 2 days ago (1 injection a day -- 40 mg). I am also taking a daily baby aspirin and folic acid. For the first time, I had some bleeding today and am very worried.

My question is if anyone has experienced any light bleeding while on Lovenox? Of course I am worried about a m/c but I am also hoping that it might have something to do with starting the injections and baby aspirin?

Any information would be greatly appreciated.
Thank you,
-Susan
[/quote] :P


StaceyK - May 1st, 2006 12:48 PM

Where do you all inject yourselves? The tummy seems to work best for me. My doc said I could inject from my thighs up to the top of my tummy.


Cici - May 1st, 2006 4:07 PM

Hi all,

I've been reading through this thread for sometime now.

I've had 6 recurrent miscarriages, the last was in March 2006 and before getting AF, we got a BFP, we are happy but conceerned also.

This is my first pregnancy on 40mg of Lovenox perday, also taking progesterone caps orally, and baby aspirin 81mg per day.

I started spotting brown yesterday (5w 0d) and today at (5w 1d) it's still just there when i wipe but it's like it's turning reddish in colour.

I just feel so down......... I feel like it's probably the start of another m/c.

Does anyone have any advice to offer?

Do you think i should stop the baby aspirin seeing as i'm using the lovenox?

Please help, I just feel so sad right now, this is my 7th pregnancy and no children.

thanks,
Cici


Cici - May 1st, 2006 7:30 PM

Hi again,

The spotting/bleeding has stopped, we're praying that it wasn't anything serious.

thanks,
Cici


aprila - May 4th, 2006 12:54 AM

Thank you Heathermac for responding and for the advice.I will try the ice to make the shots better. Susan I am glad that your bleeding has stopped. I have had three miscarragies and am now 8wks and my heart would break if I started bleeding. I try to to be sceared but it is hard. I hope everything goes good for you. BEST LUCK TO ALL OF YOU LADIES.
April


meltimaxx - May 4th, 2006 10:02 AM

Just wanted to add my 2 cents. I am 12 weeks now - have had 2 prior miscarriages. I was seeing a specialist & was just converted over to a regular OB. The specialist also put me on daily Lovenox injections along with a baby aspirin per day. I've been doing this since the pregnancy was confirmed & he told me I would continue this until a few weeks before delivery. So far, all is well - I've had some spotting here & there, but they say that's normal. The Dr. did however have to decrease my dosage of Lovenox when my spotting was bright red. With the decreased dosage, it turned to brown & lately there's been nothing. Hope this helps.


HeatherMac - May 4th, 2006 10:05 AM


StacyK,

As far as sites, I used my abdomen only. I rotated the sites with each injection and went from hip to hip...I bruised so badly on my thighs and stomach that I could only use my abdomen. By the end, I was bruised and knotted up pretty badly, but you can't tell now.

I was switched to Heparin just a few weeks before my due date because it's more surgery friendly, and the needles I was given for those injections were much more painful for some reason. The Lovenox needles are nice and sharp, and while it stings a lot and burns...I much preferred it to the Heparin.

Also, I was switched back to Lovenox for six weeks after delivery, which came as a total surprise to me...so be prepared that if that has not been discussed with you yet. I guess there is a HUGE concern for throwing a clot is after delivery, so it's actually for your health and wellbeing this time.

I hope each of you is well - keep the updates coming!! I wish you only the best!!


HeatherMac


Susan - May 4th, 2006 10:12 PM

I so appreciate reading everyone's comments and feel so grateful to have found this forum.
Cici, I am so happy to hear that the spotting/bleeding you experienced has stopped. Such good news!
Regarding the question of where we inject ourselves ... I was taught to give myself the Lovenox in either leg, from the middle point out. While it does burn, fortunately it hasn't been too bad for me. I then realized that that might be the case due to my legs having a bit more "padding" than most of yours probably do! : )
My best wishes to all of you,
-Susan


HeatherMac - May 4th, 2006 10:52 PM


HAHA!! Susan...I guess that's why I had such good luck with my abdomen as an injection site - it's padded nicely!!


rheagan - May 5th, 2006 11:00 AM

I started taking Lovenox 40mg 2x daily and a baby asprin also the day the pg was confirmed. I have had to m/c and delivered a premature baby at 24 weeks. She lived for 18 days and was such a fighter. I am 12wks and 1day now and things seem to be going well so far. I give my injections in the stomache and rotate sides every time I give an injection. I am pretty bruised and knotted up. Are all of you guys seeing a hemotologist as well as your OB?


StaceyK - May 8th, 2006 11:55 AM

::)I am not seeing a hemotologist. I am only taking lovenox 40mg once a day. I have stopped the baby asprin due to spotting. The spotting stopped after discontinuing the baby asprin. I am 18 weeks now.


HeatherMac - May 8th, 2006 2:25 PM


Rheagan,

I did not see a hemotologist, either. Just my OB, but he works very closely with an endocrinologist that I also see and together they work on fertility issues. My RE was the one who actually put me on the Lovenox the day he released me to my OB, but he knew I was being monitored, so I think he was fine with that. I have seen the endocrinologist every six weeks for three years, so I get a lot of bloodwork done anyway.


HeatherMac


Jill - May 8th, 2006 4:29 PM

I am + for Factor V. I have a daughter thats 6 and when I was 7 months they found a clot in my leg. Until the delivery I had to take 2 shots a day Lovenox first and then Heprin. I had a perfectly healthy little girl. We decided to try again and I lost my baby boy at 12 weeks just this last January. I am now pregnant again 9 weeks. I have to take 7 folic acid pills, 120 mg lovenox and progesterone pills, and prenatals. I pray this time that It works out. It is upsetting to m/c I have never felt so lost in my life. God is the only way that I made it through. Its amazing the read all the stories that you women have. It helps me to get through. The sad thing is at our church one of the other girls was due the same time as I was and I have to watch her belly grow. I am lucky to be caring another child, but I am worried all the time. Let me know how you girls feel

Thanks
JILL


HeatherMac - May 8th, 2006 9:39 PM


Jill,

I will keep you in my prayers. I know this is difficult, believe me, I know. But you're in a great support group here, so keep coming back.

I also took TONS of folic acid pills - I was on 5 folic acid and two Foltx, which is folic acid and b vitamins - along with my twice a day Lovenox injections. All the folic acid helps keep your homocystine levels down and makes your blood less sticky and prone to clotting, which helps along side the Lovenox to keep your clotting problems in check. I have too many clotting problems to list here, and I was finally successful with a healthy pregnancy - like you - thanks be to God!!

Keep us posted and keep coming back!!

HeatherMac


Tawnya - May 9th, 2006 2:42 PM

Hi, everyone!

It's so good to find other women

I am nearly 15 weeks (I had a blighted ovum in 9/05), and have been on 81mg aspirin and Heparin/Lovenox since roughly 4 weeks. My specialist told me to continue taking the aspirin with the other because it contributes to a stronger and more solidly developed placenta. I was curious, so I did research on the internet, and found lots of information backing their words up. I am also on a prenatal vitamin, in addition to the above mentioned.

I hope this helps!


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