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Sorry to be so late in getting back to you. I had a family "situation" that required my complete attention.
It is not unusual for the "lead" follicle to be bigger than the rest. There is usually a wide variation in follicular size for any patient. As long as you are lupron, you will not ovulate and a single follicle will not ovulate on its own. Ovulation during a stimulation is all-or-none. If you have an LH surge and begin to ovulate, all the follicles will ruture and release their eggs.
Ovarian stimulation in patients with PCOS is difficult to control and, if the E2 gets too high, can easily lead to hyperstimulation syndrome. In short, its very tricky. The ideal stimulation is 9-11. Eight days is the minimum for optimal results. Since you had 7, I expect that around half of the eggs will be immature (they will still be diploid) and therefore not even fertilizable. Of the ones that do fertilize normally, I expect a significant number of them will stop growing before reaching the blastocyst stage due to inadequate cytoplasmic maturity. However, that being said, there may still be one or two that will be O.K. Unfortunately, if they are transferred on Day 3, there will be no way to know if they chose the right ones. It is not until Day 4 when it becomes apparent which embryos are going to continue to growth and which ones are not.
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