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thanks doctor. i appreciate all your input. you have been wonderful throughout this process for me. I am still trying to eduacate myself on Chemical Pregnancies though. I thought this means that the embryo fails to implant or starts to implant & then is stops.

What is the cause(S) of a chemical pregnancy?

I heard that when you have endo- you may have an underlying autoimmune problem and you may have NK cells that kill off the embryo. Can this be possible? I wonder if I should do the immune testing before I waste anymore time & money.

Like you said, we do have 3 frozen- i hope that at least 2 survive. I think I might have to skip a cycle before doing this.

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A chemical pregnancy occurs when the embryo attaches, implants and begins to grow, but fails to progress. This can be caused by a problem with the embryo (usually genetic) or a problem with the endometrium (i.e. blood clotting or immune problems). Recent evidence is showing an association between endometriosis and autoimmune diseases. It is possible that endometriosis may induce abnormal NK activation. This would result in the implanting embryo being recognized as "foreign" by the NK cells and delt with accordingly. Although embryos are "foreign", the endometrium is usually a immunologically "privileged" environment that allows "foreign" tissues to grow.

I think that the immune testing is a good idea.

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