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suzsmith - March 28th, 2006 12:06 PM

Hi - I am 37 years old - just completed my first IVF cycle. My FSH is 3.9 and my estrogen levels are normal. I produced 15 follicles - 8 had eggs in them - 7 fertilized. After PGD we found out that all of the embryos were genetically abnormal. My RE thinks that this was a fluke - that we had a bad batch of eggs and that we should try again given that i stimulate well and that I am still technically young (he treats many women over 40). I am worried that I will produce only abnormal eggs and never have children of my own - is this a reasonable concern or do bad cycles sometime occur?

And - have you heard of any women who have had all abnormal eggs go on to have successful cycles?

Thanks for any help you can give....I am just heartbroken.

Suzanne

Dr Smith - March 29th, 2006 10:42 AM

I don't think you should give up just yet. Your recent cycle was just a small sample from the thousands of eggs remaining in your ovaries. However, it is likely that a significant number of the embryos resulting from a second attempt would also be abnormal. Based on available data, at 37, approximately 65-75% of the embryos will be abnormal. This solely a factor of age and has nothing to do with you personally as a patient.

Our patients (all older than you) who have had similar PGD results have moved on to successful pregnancies using donated eggs. So, I'm sorry but I don't have any encouraging news in that department.

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