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A1. The stimulation medications (FSH/LH) do not make more follicles [i]per se[/i]. That is to say, taking more more medication will not make more follicles. At the begining of a cycle, a certain number of follicles get "recruited" into the growing pool of follicles. We do not yet completely understand the mechanism of recuitment and have no medications that target the process. Accordingly, whatever starts growing is all that there's going to be on that cycle. By day 5-6 of a natural cycle, one follicle establishes dominance and the remaining follicles undergo a process called atresia (they die off). The stimulation medications (FSH/LH) act to sustain the growth of all the follicles that begin to grow on that particular cycle and prevent follicular atresia. So, there is no clear answer to your question about why you do not recruit more follicles on a given cycle, even when your FSH is normal (indicating a normal ovarian reserve). Unfortunately, its just how you are and we don't currently have a way to make your ovaries recruit more follicles on a given cycle.
A2. Probably not. The high proportion of immature eggs at the time of retrieval is a bit of a puzzle. As long as the stimulation was an adequate length (minimum of 9 days) and the peak estrogen level reflected adequate folliclular maturation (about 150-200 pg/ml E2 per mature follicle; i.e. >16 mm) and the retrieval was timed appropriately (between 34 and 36 hours after hCG, then it should have been fine. When the stimulation is adequate, we expect about 80% of the eggs to be mature at the time of retrieval. We did have a patient once that did not respond to urinary-derived hCG and all her eggs were immature at retrieval (twice!). We change to a recombinanat hCG product for the third cycle and more (but not all) of the eggs were mature. It seemed that most patients respond to urinary-derived hCG, but the occasional patient does not. You may want to discuss with your doctor or about switching brands of hCG (from recombinant to urinary-derived or vice versa).
A3. As always, its difficult to predict from Day 3 cell stage and morphology grading. Abnormal embryos rarely develop to the point where they can attach and implant (blastocyst stage). So it is highly unlikely that these embryos will result in an abnormal pregnancy (although I never say never), in the worse case, they will just stop development shortly after transfer.
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