Dr. Timothy Smith to Tangeroo
I realized that I didn't answer one of your questions.
We've never had a patient attain a successful pregnancy with a day 3 transfer after failing a day 5 transfer. However, once we changed to blastocyst transfers 2+ years ago, we have never performed a day 3 transfer.
For us, blastocyst culture and transfer has worked out great.
See below for mid-year stats for our program:
88% of our patients make it to retrieval and of those that do, 94% make it to transfer.
<36 yr old 52% ongoing pregnancy per retrieval
36-39 yr old 48% ongoing pregnancy per retrieval
40+ yr old 4/8 ongoing pregnancy (50%, but not so reliable because number of patients is low.)
Donor egg 88% ongoing pregnancy per retrieval
Last years stats weren't quite as high, (36-44% ongoing or live birth for patients <40 yr old, 63% for donor egg) but that's before I was hatching the blastocysts. Hatching made a difference.
I don't see any programs using day 3 transfers with these kinds of stats, so I think we're doing something right.